Table of Contents
Introduction
Semaglutide is a medication that has gained significant attention in recent years. It is used to treat type 2 diabetes and is also prescribed for weight loss in people with obesity. This drug belongs to a class of medications called GLP-1 receptor agonists, which help regulate blood sugar and control appetite. While semaglutide has shown great benefits for many patients, some concerns have been raised about its possible effects on the digestive system, including a potential connection to peptic ulcer disease (PUD).
Peptic ulcer disease is a condition where open sores, called ulcers, develop in the lining of the stomach or the upper part of the small intestine. These ulcers can cause pain, discomfort, and serious complications if left untreated. The most common causes of peptic ulcers include infection with Helicobacter pylori (H. pylori) bacteria, the use of certain pain medications like nonsteroidal anti-inflammatory drugs (NSAIDs), and excessive stomach acid production. However, some experts are now investigating whether semaglutide might also contribute to the development or worsening of peptic ulcers.
Since semaglutide affects the digestive system, it is important to understand how it interacts with the stomach and intestines. Some of the most common side effects of semaglutide include nausea, vomiting, diarrhea, and stomach pain. These symptoms suggest that the medication has a direct impact on the gastrointestinal (GI) tract. Because of this, researchers are asking whether semaglutide could also increase the risk of developing stomach ulcers, especially in people who already have risk factors for PUD.
The link between semaglutide and peptic ulcer disease is still being studied, and there is no clear answer yet. Some studies suggest that semaglutide may slow down digestion, which could potentially lead to increased stomach acid exposure and irritation of the stomach lining. Other reports indicate that some patients who take semaglutide experience worsening acid reflux or stomach pain, which could be early warning signs of an ulcer. However, the exact relationship between semaglutide and peptic ulcer disease is not fully understood.
This article will explore this topic in detail. It will answer common questions about semaglutide and its potential effects on peptic ulcers. It will explain what semaglutide is, how it works, and why it affects digestion. It will also describe the symptoms, causes, and risk factors for peptic ulcer disease. Additionally, the article will examine whether semaglutide can cause or worsen ulcers, what warning signs to watch for, and how to manage peptic ulcers in people taking this medication.
Understanding the possible risks of any medication is essential for both patients and healthcare providers. For people who are taking semaglutide or considering it as a treatment, it is important to be aware of any possible side effects. If semaglutide does increase the risk of peptic ulcer disease, patients need to know what steps they can take to prevent complications. Fortunately, even if there is a connection between semaglutide and ulcers, there are ways to manage and reduce the risk.
At the end of this article, readers will have a clear understanding of whether semaglutide is a hidden risk for peptic ulcers or if the concern can be managed with proper medical guidance. By discussing the latest research and expert recommendations, this article aims to provide accurate, easy-to-understand information on this important topic.
What is Semaglutide and How Does It Work?
Semaglutide is a medication used to help control blood sugar levels in people with type 2 diabetes. It is also prescribed for weight loss in people with obesity or overweight conditions. Semaglutide belongs to a class of drugs called GLP-1 receptor agonists. These drugs mimic a natural hormone in the body called glucagon-like peptide-1 (GLP-1), which plays an important role in regulating blood sugar and digestion.
How Semaglutide Works in the Body
Semaglutide affects several systems in the body, including the pancreas, stomach, liver, and brain. Each of these effects helps manage blood sugar and promote weight loss.
- Stimulating Insulin Release
- When a person eats, their blood sugar levels rise. Semaglutide helps the pancreas release more insulin in response to high blood sugar.
- Insulin is a hormone that allows sugar from food to enter cells, where it is used for energy.
- This process helps lower blood sugar levels and prevents spikes after meals.
- Reducing Glucagon Production
- The pancreas produces another hormone called glucagon, which raises blood sugar levels by telling the liver to release stored sugar.
- In people with diabetes, glucagon levels can be too high, leading to excess sugar in the blood.
- Semaglutide reduces the amount of glucagon the body makes, helping to keep blood sugar stable.
- Slowing Down Stomach Emptying
- Semaglutide slows down the movement of food from the stomach into the intestines.
- This means that food stays in the stomach longer, making people feel full for a longer time.
- As a result, it reduces hunger and helps with weight loss.
- However, this slower digestion can sometimes cause nausea, bloating, or stomach pain.
- Affecting Appetite and Brain Signals
- The brain plays a big role in hunger and eating habits.
- Semaglutide acts on the hypothalamus, a part of the brain that controls appetite.
- It helps reduce cravings and makes people feel satisfied with smaller portions of food.
- This effect makes semaglutide useful for weight loss treatments, especially in people who struggle with overeating.
Main Uses of Semaglutide
- Type 2 Diabetes Management
- Semaglutide is used to lower blood sugar levels in people with type 2 diabetes.
- It is often prescribed when other medications, such as metformin, are not enough to control blood sugar.
- Studies show that semaglutide can lower A1C levels, which is a long-term measure of blood sugar control.
- Weight Loss in Obesity and Overweight Conditions
- Semaglutide is approved for weight loss under the brand name Wegovy.
- It helps people lose weight by reducing hunger and increasing feelings of fullness.
- Many patients lose a significant amount of weight while taking semaglutide, which can improve overall health and reduce the risk of diabetes, heart disease, and high blood pressure.
Common Side Effects of Semaglutide
Since semaglutide affects digestion, it can cause some gastrointestinal side effects. These include:
- Nausea (especially when first starting the medication)
- Vomiting
- Diarrhea or constipation
- Stomach pain or bloating
Most side effects improve over time as the body gets used to the medication. However, in some cases, semaglutide may cause more serious problems, such as inflammation of the pancreas (pancreatitis) or gallbladder disease.
Why Understanding Semaglutide Matters
Semaglutide has proven to be a powerful tool for managing diabetes and weight. However, because it affects the digestive system, it may also have potential risks related to stomach and intestinal health. This is why researchers are studying its possible connection to peptic ulcer disease (PUD). Understanding how semaglutide works can help patients and doctors make informed decisions about its use.
Understanding Peptic Ulcer Disease (PUD)
Peptic ulcer disease (PUD) is a condition where open sores, or ulcers, develop in the inner lining of the stomach or the upper part of the small intestine (duodenum). These ulcers can cause pain, discomfort, and serious complications if left untreated. They form when the protective lining of the stomach or duodenum is weakened, allowing stomach acid to cause damage.
Types of Peptic Ulcers
There are two main types of peptic ulcers:
- Gastric Ulcers – These occur in the lining of the stomach. They can cause pain, especially after eating, since food triggers acid production, which can irritate the ulcer.
- Duodenal Ulcers – These develop in the first part of the small intestine, known as the duodenum. Pain from these ulcers often happens when the stomach is empty, such as at night or between meals, and may improve after eating.
While both types of ulcers involve acid damage, they can have different causes, risk factors, and treatment approaches.
Common Causes of Peptic Ulcer Disease
Several factors can lead to peptic ulcers, but the most common are infection with Helicobacter pylori (H. pylori) bacteria and long-term use of certain medications.
- H. pylori Infection
H. pylori is a type of bacteria that can live in the stomach. Many people have this infection without symptoms, but for some, it weakens the stomach lining and increases acid production, leading to ulcers. It spreads through contaminated food, water, or close contact with an infected person. The infection can remain in the stomach for years, slowly damaging the lining and making it more vulnerable to acid. - Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Medications like aspirin, ibuprofen, and naproxen are used for pain relief and inflammation. Long-term use or high doses can irritate the stomach lining and reduce protective mucus, leading to ulcers. People who take NSAIDs regularly, especially older adults, are at higher risk. - Excess Stomach Acid
Conditions like Zollinger-Ellison syndrome can cause excessive acid production, increasing the likelihood of ulcers. While rare, this condition leads to severe ulcers that are harder to treat. - Smoking and Alcohol
Smoking weakens the stomach’s ability to heal and increases acid production, making ulcers more likely. Alcohol can irritate the stomach lining, especially when consumed in large amounts or combined with other risk factors like H. pylori infection. - Stress and Diet
While stress and diet alone do not directly cause ulcers, they can make symptoms worse. Spicy foods, caffeine, and acidic foods may increase discomfort in people who already have an ulcer. Chronic stress can also affect digestion and healing, making ulcers more difficult to manage.
Symptoms and Warning Signs
The symptoms of peptic ulcer disease can vary from mild to severe. Some people may not have any symptoms until complications occur. Common symptoms include:
- Burning or gnawing stomach pain – Often felt between meals or at night, and may be relieved or worsened by eating.
- Bloating and fullness – A feeling of being uncomfortably full even after a small meal.
- Nausea or vomiting – Some people may vomit after eating, while others feel constantly nauseous.
- Dark or bloody stools – Black, tar-like stools or visible blood can indicate bleeding from an ulcer.
- Unexplained weight loss – Losing weight without trying may be a sign of a serious ulcer or another digestive issue.
Complications of Peptic Ulcers
If left untreated, peptic ulcers can lead to serious health problems, including:
- Internal bleeding – When an ulcer erodes a blood vessel, it can cause slow or sudden bleeding, leading to anemia or severe blood loss.
- Perforation – A hole in the stomach or intestinal wall, which can cause infection and severe pain. This is a medical emergency.
- Gastric obstruction – Scar tissue from ulcers can block food from passing through the digestive system, leading to vomiting and weight loss.
Understanding peptic ulcer disease is important, especially for people using medications that may increase the risk of developing ulcers. Recognizing the symptoms early and seeking medical care can prevent complications and improve quality of life.
Can Semaglutide Cause Peptic Ulcers?
Semaglutide is a medication used to treat type 2 diabetes and obesity. It belongs to a class of drugs called GLP-1 receptor agonists, which work by mimicking a natural hormone in the body. This hormone helps regulate blood sugar levels, slows digestion, and reduces appetite. While semaglutide has many benefits, some people have reported gastrointestinal side effects, leading to concerns about whether it can cause peptic ulcers.
Peptic ulcers are open sores in the lining of the stomach or upper part of the small intestine (duodenum). They develop when the protective lining of the digestive tract is weakened, allowing stomach acid to damage the tissue. If ulcers are not treated, they can cause pain, bleeding, and serious complications.
There is no strong evidence that semaglutide directly causes peptic ulcers, but it may contribute to ulcer development in some people. This happens through several possible mechanisms.
Changes in Gastric Emptying and Acid Exposure
One of semaglutide’s main effects is slowing down how quickly the stomach empties food into the small intestine. This process, called gastric emptying, helps people feel full longer and reduces how much they eat. However, when food stays in the stomach for a longer time, acid can also remain in contact with the stomach lining for an extended period. Over time, this may increase irritation and inflammation, potentially leading to ulcer formation in people who are already at risk.
In addition to slowing gastric emptying, semaglutide may affect stomach acid production. While it does not directly cause the stomach to produce more acid, delayed gastric emptying may create an environment where acid damages the stomach lining more than usual. This effect can be worse in people with existing acid-related conditions, such as gastroesophageal reflux disease (GERD) or a history of ulcers.
Effects on the Protective Lining of the Stomach
The stomach and small intestine have a mucus lining that protects them from digestive acids. This mucus barrier is important for preventing ulcers. Some researchers suggest that GLP-1 receptor agonists, including semaglutide, might alter this protective barrier. Although the exact effects are still being studied, any weakening of the mucus lining could make the stomach more vulnerable to acid damage.
For people already taking nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or aspirin, the risk is even higher. NSAIDs are known to reduce the stomach’s natural protection by decreasing mucus production and increasing acid exposure. If someone is taking semaglutide and NSAIDs together, their stomach lining may be less able to defend itself against ulcers.
Inflammation and Gut Microbiome Changes
Some studies suggest that semaglutide and other GLP-1 receptor agonists might change the balance of bacteria in the gut, also known as the gut microbiome. The gut microbiome plays an important role in digestion and immune function. If semaglutide alters this balance, it could affect how well the stomach and intestines repair themselves after damage.
Inflammation in the digestive tract is another possible concern. When food stays in the stomach longer, it can cause irritation and mild inflammation. While this may not lead to ulcers in most people, those who already have inflammatory conditions such as gastritis or H. pylori infection may be more likely to develop ulcers.
Existing Reports and Clinical Data
There have been some reports of patients developing ulcers while taking semaglutide, but large clinical trials have not found strong evidence that the drug directly causes ulcers. Instead, it may increase the risk in people who already have underlying conditions that make them prone to ulcers.
Most studies on semaglutide focus on its effectiveness for diabetes and weight loss, but its long-term effects on gastric health are still being researched. Doctors and researchers continue to monitor patients for any new side effects or complications.
Differences Between Direct Cause and Increased Risk
It is important to understand the difference between a medication directly causing a disease and it increasing the risk of a disease. While semaglutide does not appear to directly cause ulcers, it may create conditions in the stomach that make ulcers more likely in some people. This means that someone with a history of acid reflux, ulcers, or chronic stomach irritation may need to be more cautious when taking semaglutide.
Doctors usually recommend that patients with a history of ulcers take protective measures, such as using medications that reduce stomach acid (proton pump inhibitors or H2 blockers) or avoiding triggers like alcohol, spicy foods, and smoking.
The link between semaglutide and peptic ulcers is still being studied, but the current evidence suggests that the medication does not directly cause ulcers. Instead, it may increase the risk in people who already have other risk factors, such as slow gastric emptying, excessive acid exposure, or a weakened stomach lining.
People who have a history of ulcers or acid-related conditions should talk to their doctor before starting semaglutide. Monitoring for symptoms such as stomach pain, nausea, bloating, and black or bloody stools is important for catching potential issues early. If symptoms appear, adjusting the medication or taking protective treatments may help reduce risks.
Semaglutide remains a valuable medication for diabetes and weight loss, but as with all medications, patients should be aware of potential side effects and discuss any concerns with their healthcare provider.
Does Semaglutide Worsen Existing Peptic Ulcers?
Peptic ulcers are open sores that form in the lining of the stomach or the upper part of the small intestine. They can be painful and, if untreated, may lead to serious complications such as bleeding or perforation. People who already have peptic ulcers may worry about how medications like semaglutide affect their condition.
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used to manage type 2 diabetes and obesity. While it helps with weight loss and blood sugar control, it can also slow down how fast food moves through the stomach. This delay in stomach emptying may have effects on peptic ulcer disease (PUD), and it is important to understand these effects to manage the condition safely.
Gastric Motility and Acid Secretion
Semaglutide affects digestion by slowing down how quickly food leaves the stomach. This process, called delayed gastric emptying, is one of the reasons semaglutide helps people feel full longer and eat less. However, in people with peptic ulcers, this slowdown may cause stomach acid to stay in contact with the ulcer for a longer time. Since acid can irritate ulcers and delay healing, some experts worry that semaglutide could make existing ulcers worse.
Additionally, although semaglutide does not directly increase acid production, it alters digestion in ways that could affect acid levels. When food stays in the stomach longer, the stomach may continue producing acid, which could worsen ulcer symptoms. If acid builds up and is not properly neutralized, it could contribute to discomfort, pain, and irritation of an existing ulcer.
Impact on Stomach Lining and Mucosal Protection
The stomach and intestines have a protective lining made of mucus and special cells that shield them from stomach acid. In people with ulcers, this protective barrier is already weakened. Semaglutide may indirectly affect this protective lining by altering digestion, food movement, and acid exposure.
Some research suggests that GLP-1 receptor agonists, including semaglutide, have protective effects on the stomach lining. They may help reduce inflammation and improve mucus production, which could theoretically aid in ulcer healing. However, the effects vary from person to person, and in some cases, the delay in gastric emptying may lead to increased acid exposure, worsening ulcer symptoms.
Nausea, Vomiting, and Their Effects on Ulcers
One of the most common side effects of semaglutide is nausea, and some people may also experience vomiting. For people with peptic ulcers, vomiting can be particularly concerning. Frequent vomiting may worsen irritation in the stomach, increase acid exposure, and delay the healing process. It can also lead to dehydration and loss of essential minerals that help maintain stomach health.
Additionally, the strain of vomiting may cause ulcers to bleed, leading to more serious complications. If a person with peptic ulcer disease is experiencing frequent nausea or vomiting while taking semaglutide, they should speak with a healthcare provider immediately. Adjustments to the medication, diet changes, or additional treatments may be needed to manage symptoms safely.
Clinical Observations and Reports
While there is no strong clinical evidence proving that semaglutide directly causes ulcers to worsen, there have been reports of people experiencing increased gastrointestinal discomfort while using it. Some patients with pre-existing ulcers have reported worsened symptoms, including increased stomach pain, bloating, and acid reflux.
However, clinical trials of semaglutide have not found a direct link between the medication and peptic ulcer disease worsening. Most studies focus on common side effects such as nausea, vomiting, and constipation, rather than on ulcers specifically. This means more research is needed to fully understand how semaglutide interacts with peptic ulcers over time.
Considerations for People with Peptic Ulcers
People who already have peptic ulcers should be cautious when starting semaglutide. It is important to monitor symptoms closely and communicate with a healthcare provider about any changes in stomach pain, acid reflux, or digestive discomfort.
If a person has a history of ulcers but no current symptoms, a doctor may still prescribe semaglutide, but they might also recommend medications such as proton pump inhibitors (PPIs) or H2 blockers to reduce stomach acid and protect the ulcer from worsening.
For those with active ulcers, a doctor may decide to treat the ulcer first before starting semaglutide. Healing the ulcer with medications and lifestyle changes can help reduce the risk of complications once semaglutide is introduced.
Semaglutide does not directly cause ulcers, but its effects on stomach function and acid exposure could make existing ulcers worse in some cases. The delay in gastric emptying may increase irritation, while nausea and vomiting can contribute to discomfort and potential complications. People with peptic ulcers should work closely with their healthcare provider to determine the best way to manage their condition while using semaglutide. Careful monitoring, dietary adjustments, and possibly additional stomach-protective medications can help reduce risks and improve comfort while on semaglutide therapy.
Risk Factors for Peptic Ulcer Disease in Semaglutide Users
Peptic ulcer disease (PUD) is a condition in which sores develop in the lining of the stomach or the upper part of the small intestine. While semaglutide is not known to directly cause ulcers, it may increase the risk in people who already have certain risk factors. Some individuals may develop ulcers while taking semaglutide because of their medical history, lifestyle, or the use of other medications.
Understanding these risk factors is important for people using semaglutide so they can take steps to lower their chances of developing an ulcer.
Pre-existing Conditions That Increase the Risk
People who have a history of stomach or intestinal problems are more likely to develop peptic ulcers when taking semaglutide. Certain medical conditions make the stomach lining more sensitive or slow down healing, increasing the risk of ulcer formation.
- History of Peptic Ulcers: If someone has had an ulcer before, they are more likely to get another one, especially if the cause of the first ulcer was not treated completely. Semaglutide may slow digestion, increasing stomach acid exposure and delaying ulcer healing.
- Gastroesophageal Reflux Disease (GERD): GERD is a condition in which stomach acid frequently flows back into the esophagus. People with GERD often have increased stomach acid, which may contribute to ulcer development. Semaglutide may worsen acid reflux symptoms, leading to more irritation in the stomach and increasing ulcer risk.
- Gastritis (Inflammation of the Stomach Lining): Chronic gastritis weakens the stomach lining, making it more vulnerable to damage from stomach acid. Since semaglutide slows stomach emptying, it may allow acid to sit in the stomach longer, irritating the lining and increasing the risk of ulcers.
- Helicobacter Pylori (H. pylori) Infection: H. pylori is a type of bacteria that infects the stomach lining and is one of the most common causes of ulcers. People with untreated H. pylori infections are at a much higher risk of developing ulcers while on semaglutide. Testing and treatment for H. pylori may help lower this risk.
Medications That Increase the Risk of Peptic Ulcers
Certain medications can weaken the stomach lining or increase acid production, leading to ulcers. If these drugs are taken with semaglutide, the risk of developing an ulcer may be even higher.
- Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Medications like ibuprofen, aspirin, and naproxen can irritate the stomach lining and increase acid production. Long-term use of NSAIDs is a leading cause of peptic ulcers. People taking semaglutide who also use NSAIDs for pain relief or arthritis should talk to their doctor about safer alternatives.
- Corticosteroids: Drugs like prednisone, which are used to reduce inflammation in conditions like asthma, arthritis, and autoimmune diseases, can thin the stomach lining. This makes it easier for ulcers to form, especially when combined with semaglutide.
- Anticoagulants (Blood Thinners): Medications like warfarin, heparin, and newer blood thinners can make ulcers more dangerous by increasing the risk of bleeding. If someone on semaglutide develops an ulcer, these drugs can make the bleeding worse, leading to serious complications.
- SSRIs (Selective Serotonin Reuptake Inhibitors): These antidepressants, such as fluoxetine and sertraline, may increase stomach acid production, raising the risk of ulcers when combined with semaglutide.
Lifestyle Factors That Increase the Risk of Ulcers
Daily habits and lifestyle choices also play a major role in peptic ulcer disease. While semaglutide itself does not directly cause ulcers, certain behaviors may increase the risk when taking this medication.
- Diet Choices: Spicy, acidic, or highly processed foods can irritate the stomach lining and may worsen ulcer symptoms. Eating large meals or skipping meals can also contribute to acid buildup in the stomach. Since semaglutide slows digestion, it is important to eat small, balanced meals throughout the day to avoid excessive acid production.
- Smoking: Smoking weakens the protective lining of the stomach and increases stomach acid production. It also slows the healing of existing ulcers. People who smoke while taking semaglutide may be at higher risk of developing ulcers.
- Alcohol Consumption: Drinking alcohol can irritate the stomach lining and increase acid production, making it easier for ulcers to form. Alcohol also interacts with semaglutide, which can worsen nausea and stomach discomfort. Reducing alcohol intake can help protect the stomach.
- High Stress Levels: While stress alone does not cause ulcers, it can make symptoms worse by increasing stomach acid production. Chronic stress may also lead to unhealthy eating habits, such as skipping meals or consuming foods that irritate the stomach.
The Role of H. pylori and Infections
- pylori infection is one of the most common causes of peptic ulcers. This bacteria weakens the stomach lining, allowing acid to cause damage. Many people with ulcers test positive for H. pylori.
Since semaglutide affects digestion and acid exposure, people with untreated H. pylori infections may be at a higher risk of ulcer formation. Testing for H. pylori before starting semaglutide could help identify those at risk. If a person tests positive, doctors may prescribe antibiotics and acid-reducing medications to treat the infection before starting semaglutide.
Reducing the Risk of Peptic Ulcers While Taking Semaglutide
While some people may be more at risk for ulcers when using semaglutide, there are steps they can take to protect their stomach health.
- Talk to a Doctor About Your Medical History: People with a history of ulcers, GERD, or gastritis should discuss their risks with a doctor before starting semaglutide.
- Limit NSAID and Steroid Use: Using pain relievers like acetaminophen instead of NSAIDs and finding alternatives to steroids can help reduce the risk of ulcers.
- Eat a Balanced Diet: Avoiding acidic, spicy, or processed foods and eating smaller meals can reduce irritation in the stomach.
- Quit Smoking and Limit Alcohol: Both smoking and drinking alcohol can worsen stomach problems and delay healing.
- Manage Stress: Practicing relaxation techniques like deep breathing, exercise, or meditation can help reduce stomach acid production.
- Test for H. pylori: Treating an infection before starting semaglutide may lower the risk of ulcers.
People who take semaglutide should be aware of these risk factors and take precautions to protect their stomach health. Making small changes to diet and lifestyle, along with medical guidance, can help prevent peptic ulcer disease while benefiting from semaglutide’s effects.
How Can Peptic Ulcers Be Prevented While Taking Semaglutide?
Semaglutide is a medication that helps control blood sugar and supports weight loss, but it can also cause stomach-related side effects. While there is no clear proof that semaglutide directly causes peptic ulcers, it can slow down stomach emptying and increase nausea, which may make existing stomach problems worse. If someone already has a history of ulcers or other digestive issues, they may be at higher risk. However, there are ways to lower this risk and prevent ulcers from developing.
- Adjusting Semaglutide Dosage Gradually
When starting semaglutide, doctors usually recommend a low dose and slowly increase it over time. This helps the body adjust to the medication and reduces side effects like nausea and stomach discomfort. A sudden increase in dosage may cause severe stomach upset, which could irritate the stomach lining and make ulcers more likely.
If someone experiences frequent stomach pain or discomfort, their doctor may adjust the dosage or slow the increase to prevent irritation. It is important to follow the prescribed dosing schedule carefully.
- Eating the Right Foods
Diet plays a major role in ulcer prevention, especially for people taking semaglutide. Some foods can help protect the stomach lining, while others can make stomach problems worse.
- Foods that help: High-fiber foods like oats, whole grains, and vegetables can support digestion. Probiotics from yogurt or fermented foods help balance gut bacteria, which may reduce the risk of ulcers.
- Foods to avoid: Spicy, acidic, or fried foods can irritate the stomach lining. Foods high in caffeine, like coffee and chocolate, may also increase acid production, making ulcers worse.
- Eating habits: Eating smaller, more frequent meals instead of large ones can prevent stomach irritation. Drinking plenty of water can also help digestion.
- Limiting NSAIDs and Other Irritating Medications
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and aspirin, are a major cause of ulcers. They can damage the stomach lining and make ulcers more likely, especially when taken for a long time. If someone taking semaglutide also needs pain relief, they should talk to their doctor about safer options, such as acetaminophen (Tylenol), which does not harm the stomach as much.
Other medications, like corticosteroids and blood thinners, may also increase the risk of ulcers. A doctor can help determine if any medications need to be adjusted.
- Reducing Stress Levels
Long-term stress can increase stomach acid production, which may raise the risk of ulcers. While semaglutide users do not need to eliminate stress completely, managing stress in a healthy way can support stomach health.
- Relaxation techniques: Breathing exercises, meditation, or yoga can help lower stress levels.
- Physical activity: Light exercise, such as walking, swimming, or stretching, supports digestion and overall health.
- Adequate sleep: Poor sleep can increase stress and worsen digestion. Getting enough rest helps the body heal and function properly.
- Avoiding Alcohol and Smoking
Alcohol and smoking are two of the biggest risk factors for peptic ulcers. Alcohol can weaken the protective lining of the stomach, making it more vulnerable to acid damage. Smoking reduces blood flow to the stomach, slowing down healing and making ulcers more difficult to treat.
For people taking semaglutide, avoiding alcohol and quitting smoking can significantly reduce the risk of ulcers and improve overall health.
- Using Stomach-Protecting Medications If Needed
For people who have a history of ulcers or are at high risk, doctors may recommend medications that protect the stomach lining.
- Proton pump inhibitors (PPIs): These reduce stomach acid and help prevent irritation. They are often prescribed for people at risk of ulcers.
- H2 blockers: These medications also lower acid production but are less powerful than PPIs.
- Antacids: These provide quick relief from stomach pain but do not prevent ulcers.
It is important to use these medications only under a doctor’s supervision, as they can have side effects.
- Regular Medical Check-Ups and Symptom Monitoring
People taking semaglutide should have regular check-ups to ensure their stomach health is stable. If they experience symptoms like ongoing stomach pain, nausea, bloating, or dark stools, they should tell their doctor immediately. These could be signs of an ulcer, and early treatment can prevent serious complications.
A doctor may also recommend tests for H. pylori, a type of bacteria that can cause ulcers. If present, antibiotics can be used to treat the infection and prevent ulcers from developing.
Taking a Proactive Approach
By following these steps, people taking semaglutide can lower their risk of peptic ulcers and manage their digestive health effectively. Making small adjustments, such as choosing the right foods, reducing stress, avoiding NSAIDs, and staying in touch with a doctor, can help prevent serious stomach problems. While semaglutide may cause stomach discomfort in some cases, careful management can make it a safe and effective medication.
What Are the Symptoms of Peptic Ulcers While on Semaglutide?
Peptic ulcers are sores that develop on the lining of the stomach or the upper part of the small intestine. These ulcers can cause discomfort and, in some cases, serious health problems. People taking semaglutide should be aware of the symptoms of peptic ulcers, especially since the medication affects the digestive system. Recognizing the signs early can help prevent complications and ensure proper treatment.
Key Warning Signs of Peptic Ulcers
The most common symptom of a peptic ulcer is pain in the upper abdomen. This pain is often described as a burning sensation or a dull ache. It may come and go, lasting for minutes or hours. Some people notice that the pain gets worse when their stomach is empty, such as between meals or at night. Eating food or taking antacids may temporarily relieve the pain, but it usually returns.
Other symptoms that can indicate a peptic ulcer include:
- Nausea and Vomiting – Some people feel sick to their stomach or may even vomit. If vomiting is frequent or contains blood, it could be a sign of a more serious ulcer.
- Bloating and Fullness – A swollen or full feeling after eating small amounts of food is common in people with ulcers. This can be uncomfortable and may lead to a reduced appetite.
- Burping and Acid Reflux – Frequent burping, acid reflux, or heartburn may occur. These symptoms can sometimes be confused with gastroesophageal reflux disease (GERD), but they may also indicate an ulcer.
- Loss of Appetite and Weight Loss – Some people with peptic ulcers lose their desire to eat due to the discomfort caused by food. If this leads to unintended weight loss, a doctor should evaluate the cause.
- Dark Stools or Blood in the Stool – If an ulcer starts to bleed, it can cause the stool to appear dark, almost black, or have a tar-like consistency. Blood in the stool is a serious symptom that requires immediate medical attention.
- Fatigue and Weakness – Ongoing blood loss from an ulcer can lead to anemia, which may cause tiredness, weakness, dizziness, and pale skin.
When to Seek Medical Attention
Not all stomach pain means a person has a peptic ulcer. However, certain symptoms should not be ignored. A doctor should be consulted if:
- Pain is severe, persistent, or worsening over time.
- Symptoms interfere with daily life or prevent eating properly.
- Vomiting occurs frequently, especially if it contains blood or looks like coffee grounds.
- Stool is black, tarry, or contains visible blood.
- Weakness, dizziness, or fainting occurs, which could signal significant blood loss.
Ignoring peptic ulcer symptoms can lead to complications such as bleeding, stomach perforation, or a blockage in the digestive tract. Prompt medical care can help prevent these serious issues.
Distinguishing Peptic Ulcers from Common Semaglutide Side Effects
Semaglutide often causes gastrointestinal side effects, particularly in the first few weeks of use. Some of these symptoms, such as nausea, bloating, and reduced appetite, may resemble ulcer symptoms. However, there are key differences:
- Nausea from semaglutide usually occurs shortly after taking the medication and may improve as the body adjusts. Nausea from an ulcer is more likely to happen on an empty stomach or after meals.
- Bloating and fullness caused by semaglutide are often due to delayed stomach emptying. This is different from the persistent discomfort of an ulcer.
- Semaglutide-related burping and acid reflux tend to be mild and may lessen over time, whereas ulcers may cause more severe or continuous acid reflux.
- Loss of appetite from semaglutide is expected and a common reason people lose weight on the medication. If weight loss is extreme, accompanied by pain, or unrelated to appetite changes, an ulcer may be the cause.
A doctor can determine whether symptoms are due to semaglutide’s effects or an underlying peptic ulcer. If symptoms are persistent, worsen, or do not improve over time, an evaluation is necessary.
Why Awareness of Symptoms is Important
Many people using semaglutide may not initially connect their digestive symptoms to peptic ulcers. Understanding the warning signs can help individuals seek help before serious complications arise. Peptic ulcers are treatable, and most people recover fully with proper care. Those taking semaglutide should communicate any new or concerning digestive symptoms to their healthcare provider. This allows for early detection and management, ensuring both the benefits of semaglutide and overall digestive health are maintained.
How Should Peptic Ulcers Be Managed in Semaglutide Users?
Peptic ulcers are painful sores that form in the lining of the stomach or the upper part of the small intestine. When someone taking semaglutide develops a peptic ulcer, it is important to manage it properly to prevent complications like bleeding, infection, or a hole in the stomach lining. Treatment depends on the cause of the ulcer, the severity of symptoms, and whether semaglutide is contributing to the problem.
Diagnosing Peptic Ulcers in Semaglutide Users
Getting the right diagnosis is the first step in managing a peptic ulcer. Many people taking semaglutide experience nausea, stomach pain, or bloating, which can be mistaken for an ulcer. A doctor may order tests to confirm whether a person has an ulcer and determine what is causing it.
- Endoscopy – This is a procedure where a thin tube with a camera is inserted through the mouth to examine the stomach and small intestine. It helps doctors see if there is an ulcer and how severe it is.
- H. pylori Testing – A bacteria called Helicobacter pylori (H. pylori) is a common cause of ulcers. Doctors may check for this bacteria using a breath test, stool test, or a sample taken during an endoscopy.
- Blood Tests – These can check for anemia, which might suggest slow bleeding from an ulcer.
- Stool Tests – A stool sample can be tested for hidden blood, which may indicate an ulcer is bleeding.
Medications for Treating Peptic Ulcers
Once an ulcer is diagnosed, medications can help it heal. The choice of medication depends on whether the ulcer is linked to H. pylori, acid overproduction, or irritation from semaglutide’s effects on digestion.
- Proton Pump Inhibitors (PPIs) – These drugs, such as omeprazole and pantoprazole, reduce stomach acid and allow ulcers to heal. PPIs are commonly used for four to eight weeks for ulcer treatment.
- H2-Receptor Blockers – Medications like ranitidine (less common now) or famotidine reduce acid production and can help with ulcer healing.
- Antibiotics for H. pylori – If H. pylori is found, a combination of antibiotics like amoxicillin, clarithromycin, and metronidazole is used for 10–14 days to eliminate the infection.
- Mucosal Protectants – Medications like sucralfate or bismuth subsalicylate (found in Pepto-Bismol) coat the stomach lining and protect it from further damage.
Adjusting Semaglutide Dosage or Stopping Use
If semaglutide is contributing to ulcer symptoms, a doctor may decide to lower the dose or stop the medication temporarily. Some people experience relief when they switch to a lower dose and gradually increase it over time. In cases where the ulcer is severe or causing serious complications, stopping semaglutide completely may be necessary.
- Lowering the Dose – If symptoms are mild, a doctor might suggest reducing the dose and increasing it more slowly. This can help the stomach adjust to the medication.
- Temporary Pause – If an ulcer is severe, stopping semaglutide for a few weeks while treating the ulcer might be necessary. Once the ulcer heals, semaglutide may be restarted at a lower dose.
- Permanent Discontinuation – If ulcers keep coming back or if semaglutide is making them worse, a doctor may decide that another treatment is safer.
Diet and Lifestyle Changes to Help Healing
Along with medications, lifestyle changes can help ulcers heal and prevent new ones from forming. Since semaglutide affects digestion, making small changes in eating habits may reduce irritation.
- Eating Smaller, More Frequent Meals – Large meals can put extra stress on the stomach. Eating smaller portions throughout the day can reduce acid production.
- Avoiding Spicy and Acidic Foods – Foods like citrus fruits, tomatoes, coffee, and spicy meals can irritate ulcers and delay healing.
- Limiting NSAID Use – Pain relievers like ibuprofen and aspirin can weaken the stomach lining. If pain medication is needed, acetaminophen is a safer choice.
- Reducing Alcohol and Smoking – Alcohol can increase stomach acid, and smoking can slow ulcer healing. Quitting smoking and drinking less alcohol can improve recovery.
- Managing Stress – High stress levels can make ulcer symptoms worse. Techniques like meditation, gentle exercise, or therapy may help reduce stress-related stomach problems.
When to Seek Immediate Medical Attention
Some ulcer symptoms can be dangerous. A person taking semaglutide should seek medical help right away if they experience:
- Severe stomach pain that does not go away
- Vomiting blood or material that looks like coffee grounds
- Black, tarry stools (a sign of bleeding)
- Sudden dizziness, weakness, or fainting
These symptoms could mean that the ulcer is bleeding or has caused a hole in the stomach lining, which requires urgent treatment.
The Role of Healthcare Providers in Managing Peptic Ulcers
Doctors, gastroenterologists, and endocrinologists work together to create a treatment plan that balances diabetes or weight loss goals with ulcer management. Regular follow-ups can ensure that the ulcer is healing and that semaglutide is being used safely.
- Monitoring Symptoms – Checking for ongoing stomach pain or signs of worsening ulcers.
- Adjusting Treatment Plans – Changing medications if side effects are severe.
- Reassessing Semaglutide Use – Weighing the benefits of semaglutide against its risks and considering alternative medications if necessary.
Peptic ulcers in people taking semaglutide can often be managed with a combination of medications, dietary changes, and careful monitoring. Recognizing symptoms early and working closely with a doctor can help prevent complications while still benefiting from semaglutide’s effects on blood sugar and weight.
What Do Current Guidelines and Studies Say About Semaglutide and Peptic Ulcers?
Doctors and researchers have studied semaglutide for years, mostly to understand how it helps people with type 2 diabetes and obesity. While it is effective at lowering blood sugar and helping with weight loss, there is ongoing research about how it affects the stomach and intestines, including the risk of peptic ulcers. Medical guidelines help doctors decide when and how to use semaglutide, but they continue to evolve as new research emerges.
Guidelines for Semaglutide Use in Diabetes and Weight Management
Several medical organizations, including the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD), recommend semaglutide as a treatment for type 2 diabetes. The drug is also approved for weight loss in individuals with obesity or overweight who have additional health risks, such as heart disease or high blood pressure.
These guidelines highlight the benefits of semaglutide, such as lowering blood sugar, reducing appetite, and helping people lose weight. However, they also mention common side effects, mainly nausea, vomiting, and diarrhea. Some guidelines caution doctors to monitor patients with a history of gastrointestinal (GI) problems, including peptic ulcers, though ulcers are not listed as a common side effect.
The U.S. Food and Drug Administration (FDA) has approved semaglutide for both diabetes and weight loss, but its prescribing information includes warnings about its effects on digestion. The FDA label does not currently list peptic ulcers as a direct risk, but it does warn about symptoms such as severe stomach pain, vomiting, and delayed gastric emptying (slower stomach emptying), which could potentially worsen ulcers in some people.
Clinical Studies on Semaglutide and Gastrointestinal Effects
Most research on semaglutide has focused on its effectiveness in managing blood sugar and weight. However, studies have also reported a variety of side effects, particularly those affecting the digestive system.
- Gastrointestinal Side Effects in Clinical Trials
Large clinical trials for semaglutide, such as the STEP and SUSTAIN trials, tracked side effects in thousands of patients. These studies found that many people experienced nausea, vomiting, diarrhea, and constipation. Some participants reported stomach pain, but peptic ulcers were rarely mentioned as a direct side effect. - Delayed Gastric Emptying and Acid Reflux
Semaglutide slows down how quickly the stomach empties food into the intestines. While this effect helps with weight loss, it can also lead to acid reflux (heartburn) and bloating. Some researchers believe this slowdown in digestion might also increase stomach acid exposure, which could contribute to the development or worsening of ulcers in certain patients. - Case Reports of Peptic Ulcers in Semaglutide Users
Although clinical trials have not shown a strong link between semaglutide and ulcers, some doctors have reported individual cases of patients developing ulcers after starting the medication. These reports are not enough to prove that semaglutide causes ulcers, but they raise questions that require further research.
Ongoing Research and Future Studies
Since semaglutide is still a relatively new medication, researchers are continuing to study its long-term effects. Future studies will likely explore whether there is a stronger connection between semaglutide and peptic ulcers than previously thought. Some key areas of ongoing research include:
- Examining patient databases to see if people on semaglutide develop ulcers more often than those on other diabetes or weight loss medications.
- Studying how semaglutide affects stomach acid levels to determine if it increases ulcer risk.
- Identifying risk factors that make some people more likely to develop ulcers while using semaglutide.
Perspectives from Medical Experts
Doctors who specialize in diabetes (endocrinologists) and stomach disorders (gastroenterologists) are closely watching the research on semaglutide and ulcers. Many experts believe that while semaglutide is unlikely to directly cause ulcers, it may contribute to digestive problems in people who already have risk factors for ulcers, such as frequent NSAID use or H. pylori infection.
Some experts recommend that patients with a history of peptic ulcers should use semaglutide with caution and discuss potential risks with their doctor. In some cases, a doctor might prescribe medications like proton pump inhibitors (PPIs) to protect the stomach lining while a patient is taking semaglutide.
Medical guidelines support the use of semaglutide for diabetes and weight management because of its clear benefits. While studies have shown that semaglutide can cause digestive side effects, there is still no strong evidence proving that it directly causes peptic ulcers. However, doctors and researchers recognize that certain patients might be at higher risk.
Because new research continues to emerge, healthcare providers will need to stay updated on the latest studies. Patients should also be aware of potential digestive side effects and talk to their doctors about any concerns. If someone using semaglutide experiences persistent stomach pain, black stools, or vomiting that looks like coffee grounds, they should seek medical attention immediately, as these could be signs of an ulcer or internal bleeding.
More research will help determine if semaglutide is a hidden risk for ulcers or if it is simply a concern that can be managed with the right precautions. Until then, careful monitoring and good communication with a healthcare provider remain the best ways to use semaglutide safely.
Conclusion
Semaglutide is a medication that has helped many people with type 2 diabetes and obesity manage their conditions. It works by mimicking a hormone in the body called GLP-1, which helps control blood sugar levels, slows down digestion, and reduces appetite. However, like all medications, semaglutide comes with possible side effects. One area of concern is how it affects the digestive system, particularly in relation to peptic ulcer disease (PUD). Peptic ulcers are sores that develop in the stomach lining or the first part of the small intestine. They can be painful and may lead to serious complications if not properly managed.
Research on semaglutide and peptic ulcer disease is still ongoing. There is currently no clear evidence that semaglutide directly causes ulcers, but it may increase the risk in certain individuals, especially those who already have digestive issues. This could happen because semaglutide slows down how quickly food leaves the stomach. When food stays in the stomach for a longer time, acid may build up, which can irritate the stomach lining and contribute to ulcer formation.
Additionally, some people taking semaglutide may already be at higher risk for peptic ulcers. Factors such as a history of ulcers, regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, smoking, alcohol use, and stress all play a role in ulcer development. Helicobacter pylori (H. pylori), a type of bacteria, is another major cause of ulcers, and people who have this infection might be more likely to develop complications while using semaglutide.
For individuals who already have an ulcer, semaglutide may worsen symptoms. People who experience ongoing stomach pain, nausea, bloating, or black stools should contact their doctor immediately. These could be signs that an ulcer is forming or that an existing ulcer is bleeding. It is important to know the difference between normal digestive side effects of semaglutide, such as mild nausea or diarrhea, and more serious symptoms of ulcers, which include severe pain or vomiting blood.
Even though there are risks, most people can safely take semaglutide if they follow proper precautions. Preventing ulcers while using this medication includes eating a balanced diet, avoiding foods and drinks that irritate the stomach, and not taking NSAIDs unless absolutely necessary. Some doctors may recommend acid-reducing medications like proton pump inhibitors (PPIs) or H2 blockers to protect the stomach lining if a person is at high risk.
If an ulcer does develop, treatment will depend on its cause. If H. pylori bacteria are present, antibiotics may be needed to clear the infection. Acid-reducing medications can help the ulcer heal, and in some cases, adjusting the dose of semaglutide or stopping it temporarily may be necessary. However, decisions about medication changes should always be made with a doctor’s guidance.
Current medical guidelines do not list peptic ulcers as a common side effect of semaglutide, but real-world patient reports suggest that some people experience severe gastrointestinal issues. As more research is done, doctors and scientists will get a better understanding of whether semaglutide increases the risk of ulcers or simply makes existing conditions worse.
In conclusion, semaglutide does not appear to be a direct cause of peptic ulcer disease, but it may contribute to ulcer risk in people with other risk factors. The best approach is to be aware of possible symptoms, work closely with a healthcare provider, and take steps to protect digestive health. While some people may need extra monitoring, semaglutide remains a powerful treatment option for diabetes and weight loss. The key to safe use is understanding the risks and managing them properly. Future studies will continue to provide more answers, but for now, careful use and regular check-ups can help people avoid serious complications.
Research Citations
Meier, J. J., Nauck, M. A., Pott, A., et al. (2006). Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans. Gastroenterology, 130(1), 44–54. https://doi.org/10.1053/j.gastro.2005.10.004
Buckley, S. T., Bækdal, T. A., Vegge, A., et al. (2018). Transcellular stomach absorption of a derivatized glucagon-like peptide-1 receptor agonist. Science Translational Medicine, 10(434), eaar7047. https://doi.org/10.1126/scitranslmed.aar7047
Dahl, K., Brooks, A., Almazedi, F., Hoff, S. T., Boschini, C., & Baekdal, T. A. (2021). Oral semaglutide improves postprandial glucose and lipid metabolism, and delays gastric emptying, in subjects with type 2 diabetes. Diabetes, Obesity and Metabolism, 23(9), 1594–1603. https://doi.org/10.1111/dom.14373
Overgaard, R. V., Navarria, A., Ingwersen, S. H., Bækdal, T. A., & Kildemoes, R. J. (2021). Clinical pharmacokinetics of oral semaglutide: Analyses of data from clinical pharmacology trials. Clinical Pharmacokinetics, 60(11), 1335–1348. https://doi.org/10.1007/s40262-021-01025-x
Bækdal, T. A., Breitschaft, A., Navarria, A., & Hansen, C. W. (2018). A randomized study investigating the effect of omeprazole on the pharmacokinetics of oral semaglutide. Expert Opinion on Drug Metabolism & Toxicology, 14(10), 869–877. https://doi.org/10.1080/17425255.2018.1488965
Meier, J. J. (2012). GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus. Nature Reviews Endocrinology, 8(6), 728–742. https://doi.org/10.1038/nrendo.2012.140
Pratley, R., Amod, A., Hoff, S. T., et al. (2019). Oral semaglutide versus subcutaneous liraglutide and placebo in type 2 diabetes (PIONEER 4): A randomised, double-blind, phase 3a trial. The Lancet, 394(10192), 39–50. https://doi.org/10.1016/S0140-6736(19)31271-1
Aroda, V. R., Rosenstock, J., Terauchi, Y., et al. (2019). PIONEER 1: Randomized clinical trial comparing the efficacy and safety of oral semaglutide monotherapy with placebo in patients with type 2 diabetes. Diabetes Care, 42(8), 1724–1732. https://doi.org/10.2337/dc19-0749
Kim, J. H., Park, H. S., Ko, S. Y., et al. (2010). Diabetic factors associated with gastrointestinal symptoms in subjects with type 2 diabetes. World Journal of Gastroenterology, 16(14), 1782–1787. https://doi.org/10.3748/wjg.v16.i14.1782
Boehme, M. W., Autschbach, F., Ell, C., & Raeth, U. (2007). Prevalence of silent gastric ulcer, erosions or severe acute gastritis in patients with type 2 diabetes mellitus—a cross-sectional study. Hepatogastroenterology, 54(79), 643–648.
Questions and Answers: Semaglutide and Peptic Ulcer Disease
Semaglutide is a GLP-1 receptor agonist that mimics the action of glucagon-like peptide-1 (GLP-1) to regulate blood sugar levels, promote weight loss, and slow gastric emptying. It is commonly used to treat type 2 diabetes and obesity.
While semaglutide is not directly linked to peptic ulcer disease, it can cause gastrointestinal side effects such as nausea, vomiting, and delayed gastric emptying, which may exacerbate existing ulcers or contribute to discomfort in those with a history of PUD.
No, semaglutide does not directly increase gastric acid secretion. However, delayed gastric emptying may contribute to prolonged acid exposure in the stomach, which could potentially worsen symptoms in individuals prone to acid-related disorders.
Semaglutide can be used with caution in patients with a history of PUD. However, those with active ulcers or a history of severe gastrointestinal disease should consult their healthcare provider before starting treatment.
Common gastrointestinal side effects of semaglutide include nausea, vomiting, diarrhea, abdominal pain, and bloating. These symptoms can potentially aggravate existing ulcers or lead to discomfort in patients with PUD.
Yes, caution should be used. NSAIDs (such as ibuprofen and aspirin) are known to cause gastric irritation and increase the risk of ulcers. If semaglutide delays gastric emptying, this could further increase the risk of NSAID-induced ulcers.
Yes, PPIs (such as omeprazole) and H2 blockers (such as famotidine) can be used alongside semaglutide to help manage acid-related disorders and protect the stomach lining in patients with a history of PUD.
There is no direct evidence that semaglutide affects H. pylori infections. However, since H. pylori contributes to ulcer formation, patients diagnosed with an infection should receive appropriate treatment before starting semaglutide.
If a patient develops symptoms such as burning stomach pain, black stools, vomiting blood, or severe nausea, they should immediately consult their healthcare provider and consider stopping semaglutide if recommended.
Patients should avoid NSAIDs, limit alcohol, eat small meals, stay hydrated, and take ulcer-protective medications if needed. Regular monitoring and communication with a doctor are essential for safety.
Dr. Kevin Kargman
Dr. Kevin J. Kargman is a pediatrician in Sewell, New Jersey and is affiliated with multiple hospitals in the area, including Cooper University Health Care-Camden and Jefferson Health-Stratford, Cherry Hill and Washington Township. (Learn More)